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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRAF
All Species:
36.36
Human Site:
T560
Identified Species:
57.14
UniProt:
P15056
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15056
NP_004324.2
766
84437
T560
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Chimpanzee
Pan troglodytes
XP_001155024
767
84561
T560
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532749
767
85780
T560
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
P28028
804
88899
T597
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Rat
Rattus norvegicus
P11345
648
72910
A461
Q
G
M
D
Y
L
H
A
K
N
I
I
H
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516512
799
90020
T592
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Chicken
Gallus gallus
Q04982
806
89347
T600
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Frog
Xenopus laevis
P09560
638
71941
H451
A
Q
G
M
D
Y
L
H
A
K
N
I
I
H
R
Zebra Danio
Brachydanio rerio
NP_991307
777
86403
T570
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Tiger Blowfish
Takifugu rubipres
NP_001032957
778
86510
T571
L
I
D
I
A
R
Q
T
A
Q
G
M
D
Y
L
Fruit Fly
Dros. melanogaster
P11346
782
88616
V575
L
I
D
I
G
R
Q
V
A
Q
G
M
D
Y
L
Honey Bee
Apis mellifera
XP_396892
715
80060
D521
A
K
N
I
I
H
R
D
L
K
S
N
N
I
F
Nematode Worm
Caenorhab. elegans
Q07292
813
90389
K584
G
A
I
I
D
I
L
K
Q
V
S
L
G
M
N
Sea Urchin
Strong. purpuratus
XP_781094
750
85072
T543
L
I
D
I
S
R
Q
T
A
Q
G
M
D
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
H586
I
L
M
E
Q
D
F
H
A
E
R
V
N
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
92.9
N.A.
88.8
50.2
N.A.
85.7
89.8
49.3
83.5
82.9
42.8
50.6
30.7
49.3
Protein Similarity:
100
99.3
N.A.
93.4
N.A.
89.3
62.2
N.A.
86.7
90.9
61.3
87.5
87.1
57.9
65
46.6
62.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
100
100
6.6
100
100
86.6
6.6
6.6
93.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
100
33.3
100
100
86.6
33.3
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
0
54
0
0
7
80
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
7
14
7
0
7
0
0
0
0
67
0
7
% D
% Glu:
0
0
0
7
0
0
0
0
0
7
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
14
% F
% Gly:
7
7
7
0
7
0
0
0
0
0
67
0
7
0
0
% G
% His:
0
0
0
0
0
7
7
14
0
0
0
0
7
7
0
% H
% Ile:
7
67
7
80
7
7
0
0
0
0
7
14
7
7
0
% I
% Lys:
0
7
0
0
0
0
0
7
7
14
0
0
0
0
0
% K
% Leu:
67
7
0
0
0
7
14
0
7
0
0
7
0
0
67
% L
% Met:
0
0
14
7
0
0
0
0
0
0
0
67
0
7
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
7
7
14
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
0
0
7
0
67
0
7
67
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
67
7
0
0
0
7
0
0
7
7
% R
% Ser:
0
0
0
0
7
0
0
0
0
0
14
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _